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    | Meghna Ghodawa-
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    Beat the monsoon greys in style with India’s first UPF resort-wear line by Meghna Ghodawat

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    *Padma Shri Dr. Prahalad Rama Rao, Project Director (DRDO) felicitated.

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    60% of Indians Sleep less than 6 Hours Nightly as Sleep Supplements Surge 650%

    SOUL Festival Announces its Third Chapter – 9th to 13th October at Soneva Fushi

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    Viridian Financial Group Welcomes Strategic Growth Investment from TA Associates to Expand Leading Diversified Financial Services Business in Australia

    Patrick Vith, CEO of thyssenkrupp Steering (L), with Rajkumar Ravindranathan, Chief Business Officer – EMEA & RoW, LTTS (R).

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    source:Syngenta Group

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    Lulu Mall Hosts Bangalore’s Biggest Non-Alcoholic Holi Celebration

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    TECNO Gears up to Launch POVA 7 Series with Bold New Delta Interface on July 4, Exclusively on Flipkart

    60% of Indians Sleep less than 6 Hours Nightly as Sleep Supplements Surge 650%

    SOUL Festival Announces its Third Chapter – 9th to 13th October at Soneva Fushi

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    Anantha Foods Opens Its Third Outlet in Bengaluru

    Board Games & Brews: McCafé hosts community Game Night

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  • Home
  • World

    Union Minister of Finance and Corporate Affairs Smt. Nirmala Sitharaman Highlights Key Policy Measures to Promote Export-led Growth at Exim Bank’s Trade Conclave

    Tobacco control efforts protect 6.1 billion people – WHO’s new report

    MB Patil Showcases Karnataka’s Investment Potential During Denmark Roadshow

    Roche’s Lunsumio and Polivy combination significantly prolongs remission for people with relapsed or refractory large B-cell lymphoma

    | Meghna Ghodawa-
PHOTO CREDIT-

    Beat the monsoon greys in style with India’s first UPF resort-wear line by Meghna Ghodawat

    PHOTO CREDIT:The Jamaica Tourist Board (JTB)

    Jamaica Tourism Launches a Brand-New Campaign “70 Days of Jamaica Love” to Celebrate 70 Years of Jamaica

  • National
    • All
    • Economy & Politics
    • Election

    *Padma Shri Dr. Prahalad Rama Rao, Project Director (DRDO) felicitated.

    Tata ClassEdge Limited Announces Strategic Collaboration with Tata STRIVE to Bridge Education and Employability

    MiQ Sigma: Built at MiQ’s Bengaluru Centre of Excellence (CoE), the Industry’s First AI Platform That Unifies the Programmatic Ecosystem

    TECNO Gears up to Launch POVA 7 Series with Bold New Delta Interface on July 4, Exclusively on Flipkart

    60% of Indians Sleep less than 6 Hours Nightly as Sleep Supplements Surge 650%

    SOUL Festival Announces its Third Chapter – 9th to 13th October at Soneva Fushi

  • Business

    Viridian Financial Group Welcomes Strategic Growth Investment from TA Associates to Expand Leading Diversified Financial Services Business in Australia

    Patrick Vith, CEO of thyssenkrupp Steering (L), with Rajkumar Ravindranathan, Chief Business Officer – EMEA & RoW, LTTS (R).

    L&T Technology Services and thyssenkrupp Steering Business Unit Enter Into a Strategic Partnership to Establish a Global Software Hub in Pune, India

    source:Syngenta Group

    Syngenta to become global leader in biologicals; expanding nature inspired solutions for farmers

  • Health

    Apollo Cancer Centres Launches ‘CanWin’.

    Protect and Perfect: How Face Yoga and Sunscreen Can Transform Your Skin

    Panasonic-partners-with-MeitY-Nasscom-Centre

    Panasonic partners with MeitY Nasscom Centre of Excellence (CoE) to accelerate innovation in Smart Residential Living

    Herbalife Logo

    Herbalife’s Aloin Identification Method for Aloe Vera Officially Recognized by AOAC INTERNATIONAL

    “Indian patients no longer need to look abroad for advanced treatment,” said Dr. Sharat Damodar, Senior Consultant, Haematologist and Head of Adult BMT at Narayana Health City, Bengaluru and Chairman of the Oncology Collegium at Narayana Health.

    WHO issues first global guideline to improve pregnancy care for women with sickle cell disease

  • Technology
    • All
    • Environment
    • Science

    MiQ Sigma: Built at MiQ’s Bengaluru Centre of Excellence (CoE), the Industry’s First AI Platform That Unifies the Programmatic Ecosystem

    TECNO Gears up to Launch POVA 7 Series with Bold New Delta Interface on July 4, Exclusively on Flipkart

    Jockey Woman continues to shape India’s intimate wear landscape with strategic expansion

    AMD Unveils Vision for an Open AI Ecosystem, Detailing New Silicon, Software and Systems at Advancing AI 2025

    U.S. Insurers to More than Double AI Investment in the Next 3-5 Years: Wipro Report

    Union Minister for Agriculture and Farmers Welfare Shivraj Singh Chouhan to visit Hyderabad on Monday

  • Auto

    Odysse Electric Clocks 344 Units Sold in June, Records 54% Monthly Growth

    DGCA carries out comprehensive surveillance at major airports, including Delhi and Mumbai

    India Opens Doors to Global EV Giants with Portal Launch under SPMEPCI

    Force Motors along with BMW Group India Celebrates the Roll-Out of its 100,000th engine from the Chennai Plant

  • Sports

    Jockey Woman continues to shape India’s intimate wear landscape with strategic expansion

    BCCI mourns the passing of Dilip Doshi

    PHOTO CREDIT:Amruta Fadnavis

    Amruta Fadnavis Ropes in Arjun Kapoor & Nushrratt Bharuccha for Soulful Yoga Day with 1,000 Marginalised Women

    Union Minister Dr. Mansukh Mandaviya leads Fit India Sundays on Cycle in New Delhi in collaboration with Yogasana Bharat; Says Even One Pedal in cycle is Making India a Fitness Powerhouse

  • Entertainment
    Vogue Wedding Atelier presented by HSBC India at Taj Palace, New Delhi, from 8-10 August 2025

    A New Era in Luxury Weddings – Vogue Wedding Atelier Debuts in India

    GenS Life and Dowith Lit Present ‘Senior Spotlight’: Bengaluru’s Open Mic Celebration for the 55+

    PMJ Jewels Launches PMJ SuperStar Bracelet and ‘Celebrating Daughters’ Campaign

    ‘Waves’ an OTT platform that offers clean family-friendly content: Sunil Bhatiya, Deputy Director General, Doordarshan Kendra, Panaji

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    Lulu Mall Hosts Bangalore’s Biggest Non-Alcoholic Holi Celebration

  • Lifestyle
    • All
    • Food
    • Travel

    TECNO Gears up to Launch POVA 7 Series with Bold New Delta Interface on July 4, Exclusively on Flipkart

    60% of Indians Sleep less than 6 Hours Nightly as Sleep Supplements Surge 650%

    SOUL Festival Announces its Third Chapter – 9th to 13th October at Soneva Fushi

    Jockey Woman continues to shape India’s intimate wear landscape with strategic expansion

    Anantha Foods Opens Its Third Outlet in Bengaluru

    Board Games & Brews: McCafé hosts community Game Night

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Merck Opens €59 Million CDMO Facility to Address Demand for Critical Cancer Therapies

FWM by FWM
June 24, 2022
in World
0
Merck has doubled its high-potent active pharmaceutical ingredients (HPAPI) production capacity with the expansion of its facility in Verona, near Madison, Wisconsin, USA.

Merck has doubled its high-potent active pharmaceutical ingredients (HPAPI) production capacity with the expansion of its facility in Verona, near Madison, Wisconsin, USA.

  • Expansion doubles production of the most highly potent active pharmaceutical ingredients (HPAPIs)
  • Merck now one of industry’s largest manufacturers of these components globally
  • Builds on company’s 30 years’ CDMO experience with multi-step, complex, and highly potent compounds

DARMSTADT, Germany, June 23, 2022 /PRNewswire/ — Merck, a leading science and technology company, announced that its Life Science business sector has doubled its high-potent active pharmaceutical ingredients (HPAPI) production capacity with the expansion of its facility in Verona, near Madison, Wisconsin, USA. This new €59 million, 70,000 square foot facility, officially opened today, brings 50 new jobs to the area.

“There is an increasing demand for HPAPIs due to their effectiveness against cancer at lower doses and the trend towards more targeted therapeutics. Lower-doses of these therapies reduce the negative side effects for patients who are taking on this critical fight,” said Dirk Lange, head of Life Science Services, Life Science, at Merck. “Increasing capacity at our state-of-the-art CDMO facility in Verona, Wisconsin will allow us to meet the need for these key cancer treatment components.”

Cancer is the second leading cause of death worldwide1. HPAPIs are a critical element of targeted therapies due to their extremely effective cell-killing abilities at low doses, resulting in reduced side effects for patients. They are used in novel cancer therapies, including antibody drug conjugates (ADCs), which are changing the landscape of cancer treatments.

Merck has been developing multi-step, complex, and highly potent compounds for more than 30 years and continues to be an industry leader in the development and manufacture of these components. HPAPIs require specialized handling and manufacturing facilities that protect the safety of employees and their environment. Many potential life-saving treatments never make it to market in part due to the specialized handling requirements. Merck’s Verona, Wisconsin site was the second facility in the world to be SafeBridge®-certified and the company continues to meet these rigorous safety and containment requirements necessary to this day. In fact, this expansion positions Merck as one of the largest single-digit nanogram occupational exposure limit (OEL) CDMO providers in the world. HPAPIs are measured with the most potent registering less than 10 nanograms per cubic meter. Single-digit nanogram HPAPIs require highly specialized handling, which is reflected by the OEL designation.

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In addition to HPAPI production, Merck also has extensive experience developing and manufacturing ADCs. Being the first CDMO to manufacture commercially approved ADC drugs in North America, the company recently launched new technologies to advance ADC therapies. Its unique ChetoSensar™ technology gives new promise to ADCs by alleviating solubility challenges, and Merck’s new DOLCORE™ platform significantly reduces development and manufacturing time required, increasing speed-to-market by up to a year, ultimately getting needed therapies to patients quicker.

With more than 30 years of CDMO experience in the development and manufacturing of HPAPIs, linkers and mAbs, Merck offers significant expertise in both clinical and commercial manufacturing. The company also has extensive CDMO experience in viral vector, lipids, LNP and mRNA manufacturing— from pre-clinical to commercial — helping to streamline steps of drug development and production with a single, highly experienced partner. Additionally, BioReliance® contract testing services are integrated into the overall Services offering to further streamline the development path.

FWM

FWM

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